, ,

The normal physiological changes that accompany the transitional circulation after birth can have profound effects on newborns with congenital heart disease, the most prevalent group of birth defects worldwide. Detecting severe cardiovascular malformations before birth provides an opportunity for potentially life-saving care to be delivered immediately after delivery, improving postnatal outcomes,

, , ,and allowing time for parents to process the potential implications for the child and their family. Throughout most of the past century, understanding of congenital heart disease before birth was limited to post-mortem and animal studie5 The introduction of fetal echocardiography in the 1980s brought about a revolution in in-vivo prenatal diagnosis. Indeed, in most scenarios, ultrasound remains the method of choice because of its ease of use, speed, and high diagnostic accuracy. , , However, certain fetal and maternal factors can have……continue reading   https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32490-5/fulltext?dgcid=raven_jbs_etoc_email