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Tuberculosis remains the single major cause of mortality
in patients with HIV globally, accounting for an estimated
000 deaths in 2016.1 In many parts of sub-Saharan
Africa, most admitted medical inpatients are HIV-positive
and tuberculosis is the major cause of both admission
(18–29%) and in-hospital death (21–33% in cohort studies
and 32–67% in autopsy studies).2,3. Suboptimal diagnostics are an important contributor
to poor outcomes from HIV-associated tuberculosis.
Tuberculosis is commonly disseminated, presents with
non-specific clinical features, and is only diagnosed……. see more