Epilepsy is the most common neurological symptom of tuberous sclerosis complex, an autosomal dominant genetic disorder, and is reported in up to 85% of patients with the condition.1, 2 Nearly two-thirds of patients with tuberous sclerosis complex present with seizures in the first year of life, often as focal seizures or infantile spasms.1, 2 Early onset of epilepsy and particularly untreated early-onset epilepsy is associated with an increased risk of neurodevelopmental disabilities, including autism spectrum disorder and intellectual disability.2 Seizures associated with tuberous sclerosis complex can be focal, multifocal, or generalised, and are typically difficult to control.3 More than 60% of patients are….continue reading..

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31419-2/fulltext?elsca1=etoc

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